Isabella "Belle" Howard (later Isabella Weber) (c.1856-1922) was born in Zanesville, Ohio, and died in Los Angeles, California. In 1882, she inherited a boarding house at 476 Pennsylvania Avenue NW, in Washington, D.C., which had previously been run by her mother, Anna. She ran the boarding house until the late 1890s, when she moved to San Diego, California, with her husband, Julius, a retired U.S. Army Lieutenant. Although she expressed interest in Christian Science, there is no record of her studying with Mary Baker Eddy or uniting with the Church of Christ (Scientist).

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